Biotinylated Human MSLN on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Human MSLN/Mesothelin protein (Recombinant) (C-His-Avi) {Biotin} (STJP001706)

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STJP001706
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Short Description :Recombinant-Human MSLN/Mesothelin-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Host:HEK293
Note:STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Biotin
Dilution Range:Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Formulation:Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Storage Instruction:The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin:Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol:MSLN
Gene ID:10232
Uniprot ID:MSLN_HUMAN
Immunogen:DNA sequence encoding Human MSLN/Mesothelin including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Immunogen Region:Glu296-Gly580
Post Translational Modifications Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin.
Function Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Protein Name Mesothelin
Cak1 Antigen
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor
Mpf - Mesothelin - Cleaved Form
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Golgi Apparatus
Megakaryocyte-Potentiating Factor: Secreted
Isoform 3: Secreted
Alternative Protein Names Mesothelin protein
Cak1 Antigen protein
Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor protein
Mpf - Mesothelin - Cleaved Form protein
MSLN protein
MPF protein

Information sourced from Uniprot.org

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