• Human MMP-9 protein (Recombinant) (C-His) (STJP000879)
  • Human MMP-9 protein (Recombinant) (C-His) (STJP000879)
  • Human MMP-9 protein (Recombinant) (C-His) (STJP000879)
  • Human MMP-9 protein (Recombinant) (C-His) (STJP000879)

Human MMP-9 protein (Recombinant) (C-His) (STJP000879)

SKU:
STJP000879

£68.50 - £206.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human MMP-9-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured in a cell migration assay using A549 cells.1 ng/mL of Recombinant Human MMP-9 can effectively induce A549 cells migration.2. Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >1
Gene Symbol: MMP9
Gene ID: 4318
Uniprot ID: MMP9_HUMAN
Immunogen Region: Ala20-Asp707 Q279R
Immunogen: Recombinant Human MMP-9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala20-Asp707 (Q279R) ) of human MMP-9/CLG4B (Accession #NP_004985.2) fused with a 6×His tag at the C-terminus.
Tissue Specificity Detected in neutrophils (at protein level). Produced by normal alveolar macrophages and granulocytes.
Post Translational Modifications Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated.
Function Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Protein Name Matrix Metalloproteinase-9
Mmp-9
92 Kda Gelatinase
92 Kda Type Iv Collagenase
Gelatinase B
Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9
Database Links Reactome: R-HSA-1433557
Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Reactome: R-HSA-2022090
Reactome: R-HSA-3928665
Reactome: R-HSA-6785807
Reactome: R-HSA-6798695
Reactome: R-HSA-9009391
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Matrix Metalloproteinase-9 protein
Mmp-9 protein
92 Kda Gelatinase protein
92 Kda Type Iv Collagenase protein
Gelatinase B protein
Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 protein
MMP9 protein
CLG4B protein

Information sourced from Uniprot.org

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