MMADHC recombinant protein SDS-PAGE gel 3µg reducing conditions Coomassie stain

Human MMADHC protein (Recombinant) (His-Tag) (STJP018629)

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STJP018629
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Short Description :Recombinant-Human MMADHC-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:MMADHC
Gene ID:27249
Uniprot ID:MMAD_HUMAN
Accession Number:NP_056517
Immunogen:Human
Immunogen Region:39-296aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSSDESHVA AAPPDICSRT VWPDETMGPF GPQDQRFQLP GNIGFDCHLN GTASQKKSLV HKTLPDVLAE PLSSERHEFV MAQYVNEFQG NDAPVEQEIN SAETYFESAR VECAIQTCPE LLRKDFESLF PEVANGKLMI LTVTQKTKND MTVWSEEVEI EREVLLEKFI NGAKEICYAL RAEGYWADFI DPSSGLAFFG PYTNNTLF
Tissue Specificity Widely expressed at high levels.
Function Involved in cobalamin metabolism and trafficking. Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl). Promotes oxidation of cob(II)alamin bound to MMACHC. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
Protein Name Cobalamin Trafficking Protein Cbld
Cbld
Methylmalonic Aciduria And Homocystinuria Type D Protein - Mitochondrial
Database Links Reactome: R-HSA-3359473
Reactome: R-HSA-9759218
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Protein Names Cobalamin Trafficking Protein Cbld protein
Cbld protein
Methylmalonic Aciduria And Homocystinuria Type D Protein - Mitochondrial protein
MMADHC protein
C2orf25 protein
CL25022 protein
HSPC161 protein
My011 protein

Information sourced from Uniprot.org

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