| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human MBIP-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | MBIP |
| Gene ID: | 51562 |
| Uniprot ID: | MBIP1_HUMAN |
| Immunogen Region: | Leu283-Glu334 |
| Immunogen: | Homo sapiens (Human) |
| Function | Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Protein Name | Map3k12-Binding Inhibitory Protein 1Mapk Upstream Kinase-Binding Inhibitory ProteinMuk-Binding Inhibitory Protein |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusCytoplasmShows A Cytoplasmic Localization When Coexpressed With Map3k12 |
| Alternative Protein Names | Map3k12-Binding Inhibitory Protein 1 proteinMapk Upstream Kinase-Binding Inhibitory Protein proteinMuk-Binding Inhibitory Protein proteinMBIP proteinBM-015 protein |
Information sourced from Uniprot.org