Human Malate dehydrogenase 2/MDH2 protein (Recombinant) (His-Tag) (STJP016819)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Malate dehydrogenase 2/MDH2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 700unit/mg, and is defined as the amount of enzyme that cleaves 1umole of oxalacetate and beta-NADH to L-malate and beta-NAD per minute at pH8.0 at 37C. |
Target Information
| Gene Symbol | MDH2 |
| Gene ID | 4191 |
| Uniprot ID | MDHM_HUMAN |
| Accession Number | NP_005909 |
| Immunogen | Human |
| Immunogen Region | 25-338aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation by about 60%. |
| Protein Name | Malate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Malate Dehydrogenase - Mitochondrial proteinMDH2 protein |
Information sourced from Uniprot.org