Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human MAGEA1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | MAGEA1 |
Gene ID: | 4100 |
Uniprot ID: | MAGA1_HUMAN |
Immunogen Region: | Ile102-Val309 |
Immunogen: | Homo sapiens (Human) |
Function | May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. |
Protein Name | Melanoma-Associated Antigen 1Antigen Mz2-ECancer/Testis Antigen 1.1Ct1.1Mage-1 Antigen |
Cellular Localisation | CytoplasmNucleus |
Alternative Protein Names | Melanoma-Associated Antigen 1 proteinAntigen Mz2-E proteinCancer/Testis Antigen 1.1 proteinCt1.1 proteinMage-1 Antigen proteinMAGEA1 proteinMAGE1 proteinMAGE1A protein |
Information sourced from Uniprot.org