Human LYPLA2 protein (Recombinant) (C-His) (STJP014307)

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STJP014307-100
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Host: E.coli
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LYPLA2-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 1mM DTT, 100mM NaCl, pH 8.0.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: LYPLA2
Gene ID: 11313
Uniprot ID: LYPA2_HUMAN
Immunogen Region: Met1-Val231
Immunogen: Homo sapiens (Human)
Function Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
Protein Name Acyl-Protein Thioesterase 2
Apt-2
Lysophospholipase Ii
Lpl-Ii
Lysopla Ii
Palmitoyl-Protein Hydrolase
Database Links Reactome: R-HSA-373760
Cellular Localisation Cytoplasm
Alternative Protein Names Acyl-Protein Thioesterase 2 protein
Apt-2 protein
Lysophospholipase Ii protein
Lpl-Ii protein
Lysopla Ii protein
Palmitoyl-Protein Hydrolase protein
LYPLA2 protein
APT2 protein

Information sourced from Uniprot.org

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