Name: Human LTA4H protein (Recombinant) (C-His) (STJP013154)
SKU: STJP013154-100
Price: 575.5 GBP
Availability: InStock

Human LTA4H protein (Recombinant) (C-His) (STJP013154)

SKU:

STJP013154-100

£575.50

Free Shipping

Short Description :	Recombinant-Human LTA4H-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:	ELISA/WB
Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation:	Unconjugated
Formulation:	Supplied as a 0.22 Mu m filtered solution in 20mM MES, 2mM EDTA, 20% Glycerol, pH 5.0.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Phosphorylation at Ser-416 inhibits leukotriene-A4 hydrolase activity.
Function	Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4). Also has aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides. In addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions.
Protein Name	Leukotriene A-4 Hydrolase Lta-4 Hydrolase Leukotriene A(4 Hydrolase Tripeptide Aminopeptidase Lta4h
Database Links	Reactome: R-HSA-2142691 Reactome: R-HSA-6798695 Reactome: R-HSA-9018676 Reactome: R-HSA-9018681 Reactome: R-HSA-9018896 Reactome: R-HSA-9020265 Reactome: R-HSA-9023661
Cellular Localisation	Cytoplasm
Alternative Protein Names	Leukotriene A-4 Hydrolase protein Lta-4 Hydrolase protein Leukotriene A(4 Hydrolase protein Tripeptide Aminopeptidase Lta4h protein LTA4H protein LTA4 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP010844	Human LTA4H protein (Recombinant) (N-His) (STJP010844)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP019152	Human Leukotriene A4 Hydrolase/LTA4H protein (Recombinant) (His-Tag) (STJP019152)	E.coli	SDS-PAGE
STJP003629	Human F11 protein (Recombinant) (C-His) (STJP003629)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP003541	Human PTH protein (Recombinant) (C-His) (STJP003541)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB
STJP005817	Human TSLP protein (Recombinant) (C-His) (STJP005817)	Mammalian Cells	ELISA/Immunogen/SDS-PAGE/WB

Human LTA4H protein (Recombinant) (C-His) (STJP013154)

General Information