Human LETM1 protein (Recombinant) (N-His) (STJP007637)

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STJP007637
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human LETM1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: LETM1
Gene ID: 3954
Uniprot ID: LETM1_HUMAN
Immunogen Region: Leu231-Thr426
Immunogen: Homo sapiens (Human)
Function Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Functions also as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.
Protein Name Mitochondrial Proton/Calcium Exchanger Protein
Electroneutral Mitochondrial K(+/H(+Exchanger
Khe
Leucine Zipper-Ef-Hand-Containing Transmembrane Protein 1
Database Links Reactome: R-HSA-8949215
Reactome: R-HSA-9013408
Reactome: R-HSA-9865881
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Protein Names Mitochondrial Proton/Calcium Exchanger Protein protein
Electroneutral Mitochondrial K(+/H(+Exchanger protein
Khe protein
Leucine Zipper-Ef-Hand-Containing Transmembrane Protein 1 protein
LETM1 protein

Information sourced from Uniprot.org

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