Human Klotho beta/KLB protein (Recombinant) (C-His) (STJP002079)

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STJP002079
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Host:HEK293 cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:Immobilized Human Klotho at 1 Mu g/mL (100 Mu L/Well).Dose response curve for Anti-Klotho Ab.1 with the EC50 of 0.4 Mu g/ml determined by ELISA.|Immobilized Human Klotho at 2 Mu g/ml (100 Mu L/Well).Dose response curve for Anti-Klotho Ab.
Determination Method:< 1 EU/Mu g of the protein by LAL method.
Gene Symbol:KLB
Gene ID:152831
Uniprot ID:KLOTB_HUMAN
Immunogen:Recombinant Human Klotho beta/KLB Protein is produced by mammalian expression system. The target protein is expressed with sequence (Met30-Thr983) of human Beta Klotho (Accession #) fused with a His tag at the C-terminus.
Immunogen Region:Met30-Thr983
Immunogen Sequence:MSNGGLQRSVILSALILLRA VTGFSGDGRAIWSKNPNFTP VNESQLFLYDTFPKNFFWGI GTGALQVEGSWKKDGKGPSI WDHFIHTHLKNVSSTNGSSD SYIFLEKDLSALDFIGVSFY QFSISWPRLFPDGIVTVANA KGLQYYSTLLDALVLRNIEP IVTLYHWDLPLALQEKYGGW KNDTIIDIFNDYATYCFQMF GDRVKYWITIHNPYLVAWHG YGTGMHAPGEKGNLAAVYT
Protein Name Beta-Klotho
Bkl
Betaklotho
Klotho Beta-Like Protein
Database Links Reactome: R-HSA-109704
Reactome: R-HSA-1257604
Reactome: R-HSA-1307965
Reactome: R-HSA-2219530
Reactome: R-HSA-5654228
Reactome: R-HSA-5654712
Reactome: R-HSA-5654719
Reactome: R-HSA-5654720
Reactome: R-HSA-5654733
Reactome: R-HSA-5673001
Reactome: R-HSA-6811558
Cellular Localisation Cell Membrane
Single-Pass Type Iii Membrane Protein
Alternative Protein Names Beta-Klotho protein
Bkl protein
Betaklotho protein
Klotho Beta-Like Protein protein
KLB protein

Information sourced from Uniprot.org