| Short Description : | Recombinant-Human KLKB1-C-His protein was developed from mammalian cells for the region C-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | KLKB1 |
| Gene ID: | 3818 |
| Uniprot ID: | KLKB1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Met1-Ala638 |
| Function | Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Protein Name | Plasma KallikreinFletcher FactorKininogeninPlasma PrekallikreinPkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-1592389Reactome: R-HSA-9657688Reactome: R-HSA-9657689 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Plasma Kallikrein proteinFletcher Factor proteinKininogenin proteinPlasma Prekallikrein proteinPkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain proteinKLKB1 proteinKLK3 protein |
Information sourced from Uniprot.org