Human KLKB1 protein (Recombinant) (C-His) (STJP003631)

SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
STJP003631
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General Information

Short DescriptionRecombinant-Human KLKB1-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolKLKB1
Gene ID3818
Uniprot IDKLKB1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Ala638

Additional Info

Function Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Protein Name Plasma Kallikrein
Fletcher Factor
Kininogenin
Plasma Prekallikrein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain
Database Links Reactome: R-HSA-140837
Reactome: R-HSA-1592389
Reactome: R-HSA-9657688
Reactome: R-HSA-9657689
Cellular Localisation Secreted
Alternative Protein Names Plasma Kallikrein protein
Fletcher Factor protein
Kininogenin protein
Plasma Prekallikrein protein
Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain protein
KLKB1 protein
KLK3 protein

Information sourced from Uniprot.org

Citations

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