Human KLK7 protein (Recombinant) (N-GST) (STJP004839)

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STJP004839
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KLK7-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KLK7
Gene ID: 5650
Uniprot ID: KLK7_HUMAN
Immunogen Region: Glu23-Arg253
Immunogen: Homo sapiens (Human)
Function May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Protein Name Kallikrein-7
Hk7
Serine Protease 6
Stratum Corneum Chymotryptic Enzyme
Hscce
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-9725554
Cellular Localisation Secreted
In Ovarian Carcinoma
Secreted And Also Observed At The Apical Membrane And In Cytoplasm At The Invasive Front
Alternative Protein Names Kallikrein-7 protein
Hk7 protein
Serine Protease 6 protein
Stratum Corneum Chymotryptic Enzyme protein
Hscce protein
KLK7 protein
PRSS6 protein
SCCE protein

Information sourced from Uniprot.org

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