Post Translational Modifications | About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen. |
Function | Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. |
Protein Name | Kallikrein-11Hk11HippostasinSerine Protease 20Trypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2 |
Cellular Localisation | Isoform 1: SecretedIsoform 2: Golgi ApparatusSecreted |
Alternative Protein Names | Kallikrein-11 proteinHk11 proteinHippostasin proteinSerine Protease 20 proteinTrypsin-Like Protease Cleaved Into - Kallikrein-11 Inactive Chain 1 - Kallikrein-11 Inactive Chain 2 proteinKLK11 proteinPRSS20 proteinTLSP proteinUNQ649 proteinPRO1279 protein |
Information sourced from Uniprot.org