Human JSRP1 protein (Recombinant) (His-Tag) (STJP018442)

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STJP018442
€161.40 - €886.20
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human JSRP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: JSRP1
Gene ID: 126306
Uniprot ID: JSPR1_HUMAN
Immunogen Region: 1-331aa
Accession Number: NP_653217.1
Immunogen: Human
Immunogen Sequence: MSMTTRA WEELDGGLGS CQALEDHSAL AETQEDRASA TPRLADSGSV PHDSQVAEGP SVDTRPKKME KEPAARGTPG TGKERLKAGA SPRSVPARKK AQTAPPLQPP PPPPALSEEL PWGDLSLNKC LVLASLVALL GSAFQLCRDA VPGEAALQAR VPEPWVPPSS APREPSSPLP KFEAQAPPSA PPAPRAEAEV RPKIPG
Function Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.
Protein Name Junctional Sarcoplasmic Reticulum Protein 1
Junctional-Face Membrane Protein Of 45 Kda Homolog
Jp-45
Database Links
Cellular Localisation Sarcoplasmic Reticulum Membrane
Endoplasmic Reticulum Membrane
Colocalizes With Ryanodine Receptors At The Sarcoplasmic Reticulum Triad Membranes
Alternative Protein Names Junctional Sarcoplasmic Reticulum Protein 1 protein
Junctional-Face Membrane Protein Of 45 Kda Homolog protein
Jp-45 protein
JSRP1 protein
JP45 protein

Information sourced from Uniprot.org

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