| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.01 EU/Mu g |
| Gene Symbol: | CBLIF |
| Gene ID: | 2694 |
| Uniprot ID: | IF_HUMAN |
| Immunogen Region: | Ser19-Tyr417 |
| Immunogen: | Recombinant Human Intrinsic factor/CBLIF Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Ser19-Tyr417) of human Intrinsic factor/CBLIF (Accession #NP_005133.2) fused with a 6×His tag at the C-term |
| Immunogen Sequence: | STQTQSSCSVPSAQEPLVNG IQVLMENSVTSSAYPNPSIL IAMNLAGAYNLKAQKLLTYQ LMSSDNNDLTIGQLGLTIMA LTSSCRDPGDKVSILQRQME NWAPSSPNAEASAFYGPSLA ILALCQKNSEATLPIAVRFA KTLLANSSPFNVDTGAMATL ALTCMYNKIPVGSEEGYRSL FGQVLKDIVEKISMKIKDNG IIGDIYSTGLAMQALSVTPE PSKKEWNCKKTTDMILNEI |
| Function | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis. |
| Protein Name | Cobalamin Binding Intrinsic FactorGastric Intrinsic FactorIntrinsic FactorIfInf |
| Database Links | Reactome: R-HSA-3359457Reactome: R-HSA-3359462Reactome: R-HSA-3359463Reactome: R-HSA-9758881 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cobalamin Binding Intrinsic Factor proteinGastric Intrinsic Factor proteinIntrinsic Factor proteinIf proteinInf proteinCBLIF proteinGIF proteinIFMH protein |
Information sourced from Uniprot.org
