Human IL24 protein (Recombinant-Active) (C-His) (STJP012089)

SKU:
STJP012089-100
€691.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human IL24-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL24
Gene ID: 11009
Uniprot ID: IL24_HUMAN
Immunogen Region: Gln53-Leu207
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycosylated. Ubiquitination at Lys-122 promotes proteasomal degradation.
Function Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis. Possesses antiviral functions and induces the type I interferon response during influenza infection. Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1. In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1. Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal. In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2.
Protein Name Interleukin-24
Il-24
Melanoma Differentiation-Associated Gene 7 Protein
Mda-7
Suppression Of Tumorigenicity 16 Protein
Database Links Reactome: R-HSA-8854691
Cellular Localisation Secreted
Alternative Protein Names Interleukin-24 protein
Il-24 protein
Melanoma Differentiation-Associated Gene 7 Protein protein
Mda-7 protein
Suppression Of Tumorigenicity 16 Protein protein
IL24 protein
MDA7 protein
ST16 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005275 Human IL24 protein (Recombinant) (N-His) (STJP005275) E. coli
STJP011860 Human FCER1A protein (Recombinant-Active) (C-His) (STJP011860) Mammalian Cells
STJP011714 Human BTN3A3 protein (Recombinant-Active) (C-His) (STJP011714) Mammalian Cells
STJP011723 Human NCAM2 protein (Recombinant-Active) (C-His) (STJP011723) Mammalian Cells
STJP011744 Human ENTPD3 protein (Recombinant-Active) (C-His) (STJP011744) Mammalian Cells

Related Products

!