Name: Human IL-5RA/CD125 protein (Recombinant) (C-His) (STJP003097)
SKU: STJP003097
Availability: InStock

Human IL-5RA/CD125 protein (Recombinant) (C-His) (STJP003097)

SKU:

STJP003097

£89.50 - £359.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.01 EU/Mu g

Gene Symbol:	IL5RA
Gene ID:	3568
Uniprot ID:	IL5RA_HUMAN
Immunogen Region:	Met1-Glu335
Immunogen:	Recombinant Human IL-5RA/CD125 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Glu335) of human IL-5RA/CD125 (Accession #NP_000555.2) fused with and a 6×His tag at the C-terminus.
Immunogen Sequence:	SEIPKGKQKAQLRQREVVDL YNGMCLQGPAGVPGRDGSPG ANGIPGTPGIPGRDGFKGEK GECLRESFEESWTPNYKQCS WSSLNYGIDLGKIAECTFTK MRSNSALRVLFSGSLRLKCR NACCQRWYFTFNGAECSGPL PIEAIIYLDQGSPEMNSTIN IHRTSSVEGLCEGIGAGLVD VAIWVGTCSDYPKGDASTGW NSVSRIIIEELPK

Tissue Specificity	Expressed on eosinophils and basophils.
Function	Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name	Interleukin-5 Receptor Subunit Alpha Il-5 Receptor Subunit Alpha Il-5r Subunit Alpha Il-5r-Alpha Il-5ra Cdw125 Cd Antigen Cd125
Database Links	Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-912526
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Interleukin-5 Receptor Subunit Alpha protein Il-5 Receptor Subunit Alpha protein Il-5r Subunit Alpha protein Il-5r-Alpha protein Il-5ra protein Cdw125 protein Cd Antigen Cd125 protein IL5RA protein IL5R protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001466	Mouse IL-5RA/CD125 protein (Recombinant) (C-His) (STJP001466)	HEK293 cells
STJP001617	Human IL-5 R alpha/CD125 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001617)	HEK293
STJP000585	Human IL-5 receptor alpha (CD125) protein (Recombinant) (STJP000585)	HEK293
STJP001120	Human IL-7 protein (Recombinant) (C-His) (STJP001120)	HEK293 cells
STJP001306	Human IL-21 protein (Recombinant) (C-His) (STJP001306)	HEK293 cells

Human IL-5RA/CD125 protein (Recombinant) (C-His) (STJP003097)