Human IL-2 R beta/CD122 protein (Recombinant) (C-His&Avi) {Biotin} (STJP019907)

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STJP019907
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: IL2RB
Gene ID: 3560
Uniprot ID: IL2RB_HUMAN
Immunogen Region: Ala27-Asp239
Immunogen: Biotinylated Recombinant Human IL-2 R beta/CD122 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala27-Asp239) of Human IL-2 R beta/CD122 (Accession #P14784) fused with a C-His&Avi tag at the C-te
Immunogen Sequence: AVNGTSQFTCFYNSRANISC VWSQDGALQDTSCQVHAWPD RRRWNQTCELLPVSQASWAC NLILGAPDSQKLTTVDIVTL RVLCREGVRWRVMAIQDFKP FENLRLMAPISLQVVHVETH RCNISWEISQASHYFERHLE FEARTLSPGHTWEEAPLLTL KQKQEWICLETLTPDTQYEF QVRVKPLQGEFTTWSPWSQP LAFRTKPAALGKD
Function Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.
Protein Name Interleukin-2 Receptor Subunit Beta
Il-2 Receptor Subunit Beta
Il-2r Subunit Beta
Il-2rb
High Affinity Il-2 Receptor Subunit Beta
Interleukin-15 Receptor Subunit Beta
P70-75
P75
Cd Antigen Cd122
Database Links Reactome: R-HSA-5673001
Reactome: R-HSA-8983432
Reactome: R-HSA-9020558
Reactome: R-HSA-912526
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-2 Receptor Subunit Beta protein
Il-2 Receptor Subunit Beta protein
Il-2r Subunit Beta protein
Il-2rb protein
High Affinity Il-2 Receptor Subunit Beta protein
Interleukin-15 Receptor Subunit Beta protein
P70-75 protein
P75 protein
Cd Antigen Cd122 protein
IL2RB protein
IL15RB protein

Information sourced from Uniprot.org

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