| Host: | Mouse/Rabbit |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This IL-1ra/IL-1F3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: | Colormetric |
| Gene Symbol: | IL1RN |
| Gene ID: | 3557 |
| Uniprot ID: | IL1RA_HUMAN |
| Immunogen: | Capture immunogen: Recombinant Human IL-1ra/IL-1F3 protien.Detection Immunogen: Recombinant Human IL-1ra/IL-1F3 protien. |
| Sample Type: | Serum, plasma and other biological fluids |
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Pair Names | Interleukin-1 Receptor Antagonist Protein antibody pairIl-1rn antibody pairIl-1ra antibody pairIrap antibody pairIcil-1ra antibody pairIl1 Inhibitor antibody pairAnakinra antibody pairIL1RN antibody pairIL1F3 antibody pairIL1RA antibody pair |
Information sourced from Uniprot.org