Human IL-1ra/IL-1F3 (Interleukin-1 Receptor Antagonist Protein) Antibody Pair (STJAP00448)
General Information
| Short Description | This IL-1ra/IL-1F3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | IL1RN |
| Gene ID | 3557 |
| Uniprot ID | IL1RA_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human IL-1ra/IL-1F3 protien.Detection Immunogen: Recombinant Human IL-1ra/IL-1F3 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Pair Names | Interleukin-1 Receptor Antagonist Protein antibody pairIl-1rn antibody pairIl-1ra antibody pairIrap antibody pairIcil-1ra antibody pairIl1 Inhibitor antibody pairAnakinra antibody pairIL1RN antibody pairIL1F3 antibody pairIL1RA antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human IL-1ra/IL-1F3 (Interleukin-1 Receptor Antagonist Protein) Antibody Pair (STJAP00448)
This antibody pair detects human IL-1ra/IL-1F3 (Interleukin-1 Receptor Antagonist Protein), corresponding to UniProt entry P18510. Reactivity is confirmed for human samples only.
The capture antibody is supplied unconjugated at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5. The detection antibody is biotin-conjugated at 0.5 mg/mL in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5.
This pair has been validated for use in ELISA. No other assay formats are specified for this product.
This antibody pair is suitable for use with serum, plasma, and other biological fluids. These applications are for research use only and are not intended for diagnostic or therapeutic purposes.
The capture antibody was purified by Protein A or G and is mouse-derived, while the detection antibody was purified by antigen affinity and is rabbit-derived. Both antibodies were raised against recombinant human IL-1ra/IL-1F3 protein.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.