| Short Description : | Recombinant-Human IGFBP7-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 300mM NaCl, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | IGFBP7 |
| Gene ID: | 3490 |
| Uniprot ID: | IBP7_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ser27-Leu282 |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Insulin-Like Growth Factor-Binding Protein 7 proteinIbp-7 proteinIgf-Binding Protein 7 proteinIgfbp-7 proteinIgfbp-Rp1 proteinMac25 Protein proteinPgi2-Stimulating Factor proteinProstacyclin-Stimulating Factor proteinTumor-Derived Adhesion Factor proteinTaf proteinIGFBP7 proteinMAC25 proteinPSF protein |
Information sourced from Uniprot.org