| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human IGFBP-rp1/IGFBP-7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT, 1mM EDTA |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IGFBP7 |
| Gene ID: | 3490 |
| Uniprot ID: | IBP7_HUMAN |
| Immunogen Region: | 27-282aa |
| Accession Number: | NP_001544 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSSSDTCG PCEPASCPPL PPLGCLLGET RDACGCCPMC ARGEGEPCGG GGAGRGYCAP GMECVKSRKR RKGKAGAAAG GPGVSGVCVC KSRYPVCGSD GTTYPSGCQL RAASQRAESR GEKAITQVSK GTCEQGPSIV TPPKDIWNVT GAQVYLSCEV IGIPTPVLIW NKVKRGHYGV QRTELLPGDR DNLAIQTRGG PEKHEVTG |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Insulin-Like Growth Factor-Binding Protein 7 proteinIbp-7 proteinIgf-Binding Protein 7 proteinIgfbp-7 proteinIgfbp-Rp1 proteinMac25 Protein proteinPgi2-Stimulating Factor proteinProstacyclin-Stimulating Factor proteinTumor-Derived Adhesion Factor proteinTaf proteinIGFBP7 proteinMAC25 proteinPSF protein |
Information sourced from Uniprot.org
