• Human IGFBP-7 protein (Recombinant) (N-His) (STJP002393)
  • Human IGFBP-7 protein (Recombinant) (N-His) (STJP002393)

Human IGFBP-7 protein (Recombinant) (N-His) (STJP002393)

SKU:
STJP002393

£97.50 - £291.50
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: Less than 1 EU per Mu g by the LAL method.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized human IGFBP7 at 2 Mu g/mL (100 Mu L/well) can bind human CD93 with a linear range of 0.17-290.4 ng/mL.
Gene Symbol: IGFBP7
Gene ID: 3490
Uniprot ID: IBP7_HUMAN
Immunogen Region: Asp30-Leu282
Immunogen: Recombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Asp30-Leu282
Immunogen Sequence: DTCGPCEPASCPPLPPLGCL LGETRDACGCCPMCARGEGE PCGGGGAGRGYCAPGMECVK SRKRRKGKAGAAAGGPGVSG VCVCKSRYPVCGSDGTTYPS GCQLRAASQRAESRGEKAIT QVSKGTCEQGPSIVTPPKDI WNVTGAQVYLSCEVIGIPTP VLIWNKVKRGHYGVQRTELL PGDRDNLAIQTRGGPEKHEV TGWVLVSPLSKEDAGEYECH ASNSQGQASASAKITVVDA
Function Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis.
Protein Name Insulin-Like Growth Factor-Binding Protein 7
Ibp-7
Igf-Binding Protein 7
Igfbp-7
Igfbp-Rp1
Mac25 Protein
Pgi2-Stimulating Factor
Prostacyclin-Stimulating Factor
Tumor-Derived Adhesion Factor
Taf
Database Links Reactome: R-HSA-2559582
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Protein Names Insulin-Like Growth Factor-Binding Protein 7 protein
Ibp-7 protein
Igf-Binding Protein 7 protein
Igfbp-7 protein
Igfbp-Rp1 protein
Mac25 Protein protein
Pgi2-Stimulating Factor protein
Prostacyclin-Stimulating Factor protein
Tumor-Derived Adhesion Factor protein
Taf protein
IGFBP7 protein
MAC25 protein
PSF protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance