Name: Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP002854)
SKU: STJP002854
Availability: InStock

Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP002854)

SKU:

STJP002854

£97.50 - £291.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	<0.1 EU/Mu g

Gene Symbol:	IFNGR2
Gene ID:	3460
Uniprot ID:	INGR2_HUMAN
Immunogen Region:	Ser28-Asp240
Immunogen:	Recombinant Human IFN-gamma R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser28-Asp240) of human IFN-gamma R2 (Accession #NP_005525.2) fused with and a RaFc tag at the C-terminus.
Immunogen Sequence:	SQLPAPQHPKIRLYNAEQVL SWEPVALSNSTRPVVYQVQF KYTDSKWFTADIMSIGVNCT QITATECDFTAASPSAGFPM DFNVTLRLRAELGALHSAWV TMPWFQHYRNVTVGPPENIE VTPGEGSLIIRFSSPFDIAD TSTAFFCYYVHYWEKGGIQQ VKGPFRSNSISLDNLKPSRV YCLQVQAQLLWNKSNIFRVG HLSNISCYETMAD

Function	Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding.
Protein Name	Interferon Gamma Receptor 2 Ifn-Gamma Receptor 2 Ifn-Gamma-R2 Interferon Gamma Receptor Accessory Factor 1 Af-1 Interferon Gamma Receptor Beta-Chain Ifn-Gamma-R-Beta Interferon Gamma Transducer 1
Database Links	Reactome: R-HSA-877300 Reactome: R-HSA-877312 Reactome: R-HSA-9679191 Reactome: R-HSA-9732724
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cytoplasmic Vesicle Membrane Golgi Apparatus Membrane Endoplasmic Reticulum Membrane Cytoplasm Has Low Cell Surface Expression And High Cytoplasmic Expression In T Cells The Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling
Alternative Protein Names	Interferon Gamma Receptor 2 protein Ifn-Gamma Receptor 2 protein Ifn-Gamma-R2 protein Interferon Gamma Receptor Accessory Factor 1 protein Af-1 protein Interferon Gamma Receptor Beta-Chain protein Ifn-Gamma-R-Beta protein Interferon Gamma Transducer 1 protein IFNGR2 protein IFNGT1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001518	Human CD8a protein (Recombinant) (C-raFc) (STJP001518)	HEK293 cells
STJP001964	Human GHRL/MTLRP protein (Recombinant) (C-RaFC) (STJP001964)	HEK293 cells
STJP002598	Human IFN-gamma R1/CD119 protein (Recombinant) (C-His) (STJP002598)	HEK293 cells
STJP001917	Rat IFN-gamma protein (Recombinant) (C-6His) (STJP001917)	HEK293 cells
STJP001590	Human IFN gamma/IFNG protein (Recombinant) (C-His-Avi) {Biotin} (STJP001590)	HEK293

Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP002854)