Human IFN-alpha I/IFN17 protein (Recombinant) (C-6His) (STJP002938)

SKU:
STJP002938

Current Stock:
Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.01 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured in a cell cytotoxicity assay using TF-1 cells. The ED50 for this effect is 0.17‑0.68 ng/mL, corresponding to a specific activity of 1.47×106~5.88×106 units/mg.
Gene Symbol: IFNA17
Gene ID: 3451
Uniprot ID: IFN17_HUMAN
Immunogen Region: Cys24-Asp189
Immunogen: Recombinant Human IFN-alpha I/IFN17 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys24-Asp189) of Human IFN-alpha I/IFN17 (Accession #NP_067091.1) fused with a His tag at the C-terminus.
Immunogen Sequence: NWIDVRYDLEKIESLIQSIH IDTTLYTDSDFHPSCKVTAM NCFLLELQVILHEYSNMTLN ETVRNVLYLANSTLSSNKNV AESGCKECEELEEKTFTEFL QSFIRIVQMFINTS
Function Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Protein Name Interferon Alpha-17
Ifn-Alpha-17
Interferon Alpha-88
Interferon Alpha-I'
Leif I
Interferon Alpha-T
Database Links Reactome: R-HSA-909733
Reactome: R-HSA-912694
Reactome: R-HSA-933541
Reactome: R-HSA-9705671
Reactome: R-HSA-983231
Reactome: R-HSA-9833109
Cellular Localisation Secreted
Alternative Protein Names Interferon Alpha-17 protein
Ifn-Alpha-17 protein
Interferon Alpha-88 protein
Interferon Alpha-I' protein
Leif I protein
Interferon Alpha-T protein
IFNA17 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance