Human IDS/Idursulfase protein (Recombinant-Active) (C-10*His) (STJP011926)

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STJP011926-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human IDS/Idursulfase-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IDS
Gene ID: 3423
Uniprot ID: IDS_HUMAN
Immunogen Region: Ser26-Pro550
Immunogen: Homo sapiens (Human)
Post Translational Modifications Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
Function Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.
Protein Name Iduronate 2-Sulfatase
Alpha-L-Iduronate Sulfate Sulfatase
Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain
Database Links Reactome: R-HSA-2024096
Reactome: R-HSA-2024101
Reactome: R-HSA-2206296
Cellular Localisation Lysosome
Alternative Protein Names Iduronate 2-Sulfatase protein
Alpha-L-Iduronate Sulfate Sulfatase protein
Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain protein
IDS protein
SIDS protein

Information sourced from Uniprot.org