Human I-TAC/CXCL11 protein (Recombinant) (His-Tag) (STJP017420)

SKU:
STJP017420
€168.13 - €923.13
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human I-TAC/CXCL11-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 10mM Sodium Citrate buffer (pH 3.5) containing 2mM DTT, 20% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol: CXCL11
Gene ID: 6373
Uniprot ID: CXL11_HUMAN
Immunogen Region: 22-94aa
Accession Number: NP_005400
Immunogen: Human
Immunogen Sequence: FPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF
Tissue Specificity High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
Function Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Protein Name C-X-C Motif Chemokine 11
Beta-R1
H174
Interferon Gamma-Inducible Protein 9
Ip-9
Interferon-Inducible T-Cell Alpha Chemoattractant
I-Tac
Small-Inducible Cytokine B11
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-X-C Motif Chemokine 11 protein
Beta-R1 protein
H174 protein
Interferon Gamma-Inducible Protein 9 protein
Ip-9 protein
Interferon-Inducible T-Cell Alpha Chemoattractant protein
I-Tac protein
Small-Inducible Cytokine B11 protein
CXCL11 protein
ITAC protein
SCYB11 protein
SCYB9B protein

Information sourced from Uniprot.org