Human HTR6 protein (Recombinant) (N-His-KSI) (STJP015774)

SKU:
STJP015774
£222.50 - £1,177.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HTR6-N-His-KSI protein was developed from e.coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: HTR6
Gene ID: 3362
Uniprot ID: 5HT6R_HUMAN
Immunogen Region: Pro321-Asn440
Immunogen: Homo sapiens (Human)
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Also has a high affinity for tricyclic psychotropic drugs. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR6 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity. Is an activator of mTOR signaling.
Protein Name 5-Hydroxytryptamine Receptor 6
5-Ht-6
5-Ht6
Serotonin Receptor 6
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names 5-Hydroxytryptamine Receptor 6 protein
5-Ht-6 protein
5-Ht6 protein
Serotonin Receptor 6 protein
HTR6 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP011692 Human APOL1 protein (Recombinant) (N-His-KSI) (STJP011692) E.coli ELISA/WB
STJP014297 Human SOAT2 protein (Recombinant) (N-His-KSI) (STJP014297) E.coli ELISA/WB
STJP015419 Human HAND2 protein (Recombinant) (N-His-KSI) (STJP015419) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP015208 Human AQP1 protein (Recombinant) (N-His-KSI) (STJP015208) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP015281 Human SLPI protein (Recombinant) (N-His-KSI) (STJP015281) E.coli ELISA/Immunogen/SDS-PAGE/WB

Related Products

!