Human HPR protein (Recombinant) (His-Tag) (STJP018680)

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STJP018680
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HPR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH8.5) containing 20% Glycerol, 1mM DTT, 0.15M NaCl
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: HPR
Gene ID: 3250
Uniprot ID: HPTR_HUMAN
Immunogen Region: 20-348aa
Accession Number: NP_066275
Immunogen: Human
Immunogen Sequence: LYSGNDV TDISDDRFPK PPEIANGYVE HLFRYQCKNY YRLRTEGDGV YTLNDKKQWI NKAVGDKLPE CEAVCGKPKN PANPVQRILG GHLDAKGSFP WQAKMVSHHN LTTGATLINE QWLLTTAKNL FLNHSENATA KDIAPTLTLY VGKKQLVEIE KVVLHPNYHQ VDIGLIKLKQ KVLVNERVMP ICLPSKNYAE VGRVGY
Tissue Specificity In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines.
Function Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.
Protein Name Haptoglobin-Related Protein
Database Links Reactome: R-HSA-2168880
Cellular Localisation Secreted
Secreted Into Blood Plasma And Associated With Subtypes Of High Density Lipoproteins (Hdl)
Alternative Protein Names Haptoglobin-Related Protein protein
HPR protein

Information sourced from Uniprot.org

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