| Short Description : | Recombinant-Human HOXA9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HOXA9 |
| Gene ID: | 3205 |
| Uniprot ID: | HXA9_HUMAN |
| Accession Number: | NP_689952 |
| Immunogen: | Human |
| Immunogen Region: | 1-272aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMATTGAL GNYYVDSFLL GADAADELSV GRYAPGTLGQ PPRQAATLAE HPDFSPCSFQ SKATVFGASW NPVHAAGANA VPAAVYHHHH HHPYVHPQAP VAAAAPDGRY MRSWLEPTPG ALSFAGLPSS RPYGIKPEPL SARRGDCPTL DTHTLSLTDY ACGSPPVDRE KQPSEGAFSE NNAENESGGD KPPIDPNNPA ANWLHARS |
| Post Translational Modifications | Methylated on Arg-140 by PRMT5.methylation is critical for E-selectin induction. |
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation. Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH. |
| Protein Name | Homeobox Protein Hox-A9Homeobox Protein Hox-1g |
| Database Links | |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Protein Names | Homeobox Protein Hox-A9 proteinHomeobox Protein Hox-1g proteinHOXA9 proteinHOX1G protein |
Information sourced from Uniprot.org
