Name: Human HEXIM1 protein (Recombinant) (N-His) (STJP015213)
SKU: STJP015213
Availability: InStock

Human HEXIM1 protein (Recombinant) (N-His) (STJP015213)

SKU:

STJP015213

£222.50 - £1,177.50

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Host:	E.coli
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human HEXIM1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:	Please contact us for further information.

Function	Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
Protein Name	Protein Hexim1 Cardiac Lineage Protein 1 Estrogen Down-Regulated Gene 1 Protein Hexamethylene Bis-Acetamide-Inducible Protein 1 Menage A Quatre Protein 1
Database Links
Cellular Localisation	Nucleus Cytoplasm Binds Alpha-Importin And Is Mostly Nuclear
Alternative Protein Names	Protein Hexim1 protein Cardiac Lineage Protein 1 protein Estrogen Down-Regulated Gene 1 Protein protein Hexamethylene Bis-Acetamide-Inducible Protein 1 protein Menage A Quatre Protein 1 protein HEXIM1 protein CLP1 protein EDG1 protein HIS1 protein MAQ1 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP007671	Human HEXIM1 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007671)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP014592	Human PITPNA protein (Recombinant) (N-His) (STJP014592)	E.coli	ELISA/WB
STJP014658	Human HFE protein (Recombinant) (N-His) (STJP014658)	E.coli	ELISA/WB

Human HEXIM1 protein (Recombinant) (N-His) (STJP015213)

General Information