| Tissue Specificity | Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta. |
| Function | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. |
| Protein Name | Haus Augmin-Like Complex Subunit 1Coiled-Coil Domain-Containing Protein 5Enhancer Of Invasion-ClusterHei-C |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleSpindle PoleLocalizes With The Spindle Poles In Mitotic CellsIn MetaphaseLocalizes To The Mitotic Asters And Is Highly Punctate On The Microtubule ArrayDuring Later Stages Of MitosisRemains On The Spindle But Is Not Present At The InterzoneAnd Is Finally Observed At The Microtubule Bundles Proximal To The MidbodyClearly Excluded From The MidbodyIn ContrastDoes Not Colocalize With The Tubulin Cytoskeleton In Interphase CellsIn InterphaseLocalized At The Centrosome And Diffusely In The CytoplasmLocalizes To Mitotic Spindle Microtubules |
| Alternative Protein Names | Haus Augmin-Like Complex Subunit 1 proteinCoiled-Coil Domain-Containing Protein 5 proteinEnhancer Of Invasion-Cluster proteinHei-C proteinHAUS1 proteinCCDC5 proteinHEIC protein |
Information sourced from Uniprot.org
