| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human H3C15-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | H3C15.H3C14.H3C13 |
| Gene ID: | 126961/333932/653604 |
| Uniprot ID: | H32_HUMAN |
| Immunogen Region: | Met1-Ala136 |
| Immunogen: | Homo sapiens (Human) |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.2H3-Clustered Histone 13H3-Clustered Histone 14H3-Clustered Histone 15Histone H3/MHistone H3/O |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-1912408Reactome: R-HSA-201722Reactome: R-HSA-212300Reactome: R-HSA-2299718Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-3214815Reactome: R-HSA-3214841Reactome: R-HSA-3214842Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-3247509Reactome: R-HSA-427359Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5334118Reactome: R-HSA-5578749Reactome: R-HSA-5617472Reactome: R-HSA-5625886Reactome: R-HSA-68616Reactome: R-HSA-73728Reactome: R-HSA-73772Reactome: R-HSA-8936459Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-912446Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9616222Reactome: R-HSA-9710421Reactome: R-HSA-977225Reactome: R-HSA-9821002Reactome: R-HSA-983231Reactome: R-HSA-9843940Reactome: R-HSA-9843970Reactome: R-HSA-9845323 |
| Cellular Localisation | NucleusChromosome |
| Alternative Protein Names | Histone H3.2 proteinH3-Clustered Histone 13 proteinH3-Clustered Histone 14 proteinH3-Clustered Histone 15 proteinHistone H3/M proteinHistone H3/O proteinH3C15 proteinHIST2H3A.H3C14 proteinH3F2 proteinH3FM proteinHIST2H3C.H3C13 proteinHIST2H3D protein |
Information sourced from Uniprot.org