| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GZMH-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GZMH |
| Gene ID: | 2999 |
| Uniprot ID: | GRAH_HUMAN |
| Immunogen Region: | Glu19-Leu246 |
| Immunogen: | Homo sapiens (Human) |
| Function | Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. |
| Protein Name | Granzyme HCcp-XCathepsin G-Like 2Ctsgl2Cytotoxic T-Lymphocyte ProteinaseCytotoxic Serine Protease CCsp-C |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-381426 |
| Cellular Localisation | Cytolytic Granule |
| Alternative Protein Names | Granzyme H proteinCcp-X proteinCathepsin G-Like 2 proteinCtsgl2 proteinCytotoxic T-Lymphocyte Proteinase proteinCytotoxic Serine Protease C proteinCsp-C proteinGZMH proteinCGL2 proteinCTSGL2 protein |
Information sourced from Uniprot.org