Human GZMH protein (Recombinant) (N-His) (STJP004290)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GZMH-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | GZMH |
| Gene ID | 2999 |
| Uniprot ID | GRAH_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu19-Leu246 |
Additional Info
| Function | Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication. |
| Protein Name | Granzyme HCcp-XCathepsin G-Like 2Ctsgl2Cytotoxic T-Lymphocyte ProteinaseCytotoxic Serine Protease CCsp-C |
| Database Links | Reactome: R-HSA-2022377Reactome: R-HSA-381426 |
| Cellular Localisation | Cytolytic Granule |
| Alternative Protein Names | Granzyme H proteinCcp-X proteinCathepsin G-Like 2 proteinCtsgl2 proteinCytotoxic T-Lymphocyte Proteinase proteinCytotoxic Serine Protease C proteinCsp-C proteinGZMH proteinCGL2 proteinCTSGL2 protein |
Information sourced from Uniprot.org