| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20 mM Tris, 150 mM NaCl, 10% Glycerol, pH 8.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Immunoreactivity: | 1.Measured by its binding ability in a functional ELISA. Immobilized Human GSTO1 at 1 Mu g/mL (100 Mu L/well) can bind GSTO1 Rabbit mAb with a linear range of 0.5-4.33 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized Human |
| Gene Symbol: | GSTO1 |
| Gene ID: | 9446 |
| Uniprot ID: | GSTO1_HUMAN |
| Immunogen: | Recombinant Human GSTO-1/SPG-R Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser2-Leu241) of human GSTO1 (Accession #NP_004823.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | SGESARSLGKGSAPPGPVPE GSIRIYSMRFCPFAERTRLV LKAKGIRHEVININLKNKPE WFFKKNPFGLVPVLENSQGQ LIYESAITCEYLDEAYPGKK LLPDDPYEKACQKMILELFS KVPSLVGSFIRSQNKEDYAG LKEEFRKEFTKLEEVLTNKK TTFFGGNSISMIDYLIWPWF ERLEAMKLNECVDHTPKLKL WMAAMKEDPTVSALLTSEKD WQGFLELYLQNSPEACDYG |
| Function | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. |
| Protein Name | Glutathione S-Transferase Omega-1Gsto-1Glutathione S-Transferase Omega 1-1Gsto 1-1Glutathione-Dependent Dehydroascorbate ReductaseMonomethylarsonic Acid ReductaseMma(V ReductaseS-(Phenacylglutathione ReductaseSpg-R |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-156590Reactome: R-HSA-196836Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Glutathione S-Transferase Omega-1 proteinGsto-1 proteinGlutathione S-Transferase Omega 1-1 proteinGsto 1-1 proteinGlutathione-Dependent Dehydroascorbate Reductase proteinMonomethylarsonic Acid Reductase proteinMma(V Reductase proteinS-(Phenacylglutathione Reductase proteinSpg-R proteinGSTO1 proteinGSTTLP28 protein |
Information sourced from Uniprot.org
