Human GPX1 protein (Recombinant) (N-His) (STJP003776)

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STJP003776
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Short Description :Recombinant-Human GPX1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:GPX1
Gene ID:2876
Uniprot ID:GPX1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Thr50-Ala202
Post Translational Modifications During periods of oxidative stress, Sec-49 may react with a superoxide radical, irreversibly lose hydroselenide and be converted to dehydroalanine.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway.
Protein Name Glutathione Peroxidase 1
Gpx-1
Gshpx-1
Cellular Glutathione Peroxidase
Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142712
Reactome: R-HSA-2142770
Reactome: R-HSA-3299685
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Protein Names Glutathione Peroxidase 1 protein
Gpx-1 protein
Gshpx-1 protein
Cellular Glutathione Peroxidase protein
Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1 protein
GPX1 protein

Information sourced from Uniprot.org

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