Mouse GPX1 protein (Recombinant) (N-His) (STJP011092)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse GPX1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | Gpx1 |
| Gene ID | 14775 |
| Uniprot ID | GPX1_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Gly48-Ser201 |
Additional Info
| Post Translational Modifications | During periods of oxidative stress, Sec-47 may react with a superoxide radical, irreversibly lose hydroselenide and be converted to dehydroalanine. |
| Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway. |
| Protein Name | Glutathione Peroxidase 1Gpx-1Gshpx-1Cellular Glutathione PeroxidasePhospholipid-Hydroperoxide Glutathione Peroxidase Gpx1Selenium-Dependent Glutathione Peroxidase 1 |
| Database Links | Reactome: R-MMU-2142712Reactome: -MMU-2142770Reactome: -MMU-3299685 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Protein Names | Glutathione Peroxidase 1 proteinGpx-1 proteinGshpx-1 proteinCellular Glutathione Peroxidase proteinPhospholipid-Hydroperoxide Glutathione Peroxidase Gpx1 proteinSelenium-Dependent Glutathione Peroxidase 1 proteinGpx1 protein |
Information sourced from Uniprot.org