Human GPR177/WLS protein (Recombinant) (His-Tag) (STJP018122)

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STJP018122
€161.40 - €886.20
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GPR177/WLS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: WLS
Gene ID: 79971
Uniprot ID: WLS_HUMAN
Immunogen Region: 101-232aa
Accession Number: NP_079187
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEMSPWF QFMLFILQLD IAFKLNNQIR ENAEVSMDVS LAYRDDAFAE WTEMAHERVP RKLKCTFTSP KTPEHEGRYY ECDVLPFMEI GSVAHKFYLL NIRLPVNEKK KINVGIGEIK DIRLVGIHQN GGFTK
Post Translational Modifications N-glycosylated.
Function Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
Protein Name Protein Wntless Homolog
Integral Membrane Protein Gpr177
Protein Evenness Interrupted Homolog
Evi
Putative Nf-Kappa-B-Activating Protein 373
Database Links Reactome: R-HSA-3238698
Cellular Localisation Golgi Apparatus Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Cell Membrane
Endoplasmic Reticulum Membrane
Early Endosome Membrane
Co-Localizes With The Adaptin Ap2a2 At Distinct Punctae
Alternative Protein Names Protein Wntless Homolog protein
Integral Membrane Protein Gpr177 protein
Protein Evenness Interrupted Homolog protein
Evi protein
Putative Nf-Kappa-B-Activating Protein 373 protein
WLS protein
C1orf139 protein
GPR177 protein
UNQ85 protein
PRO18667 protein

Information sourced from Uniprot.org

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