Human GMPR2 protein (Recombinant) (His-Tag) (STJP016844)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GMPR2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GMPR2 |
| Gene ID | 51292 |
| Uniprot ID | GMPR2_HUMAN |
| Accession Number | NP_001002002 |
| Immunogen | Human |
| Immunogen Region | 1-348aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes. |
| Function | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. |
| Protein Name | Gmp Reductase 2Gmpr 2Guanosine 5'-Monophosphate Oxidoreductase 2Guanosine Monophosphate Reductase 2 |
| Database Links | Reactome: R-HSA-74217 |
| Cellular Localisation | |
| Alternative Protein Names | Gmp Reductase 2 proteinGmpr 2 proteinGuanosine 5'-Monophosphate Oxidoreductase 2 proteinGuanosine Monophosphate Reductase 2 proteinGMPR2 protein |
Information sourced from Uniprot.org