SDS-PAGE gel showing recombinant human GMPR2 protein 3µg under reducing conditions with Coomassie blue stain

Human GMPR2 protein (Recombinant) (His-Tag) (STJP016844)

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STJP016844
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Short Description :Recombinant-Human GMPR2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:GMPR2
Gene ID:51292
Uniprot ID:GMPR2_HUMAN
Accession Number:NP_001002002
Immunogen:Human
Immunogen Region:1-348aa
Immunogen Sequence: MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI GPGSVCTTRK KTGVGYPQLS AVMECA
Tissue Specificity Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes.
Function Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation.
Protein Name Gmp Reductase 2
Gmpr 2
Guanosine 5'-Monophosphate Oxidoreductase 2
Guanosine Monophosphate Reductase 2
Database Links Reactome: R-HSA-74217
Cellular Localisation
Alternative Protein Names Gmp Reductase 2 protein
Gmpr 2 protein
Guanosine 5'-Monophosphate Oxidoreductase 2 protein
Guanosine Monophosphate Reductase 2 protein
GMPR2 protein

Information sourced from Uniprot.org

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