Human Glycogenin 1 protein (Recombinant) (His-T7-Tag) (STJP016492)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glycogenin 1-His-T7-Tag protein was developed from e.coli and has a target region of His-T7-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GYG1 |
| Gene ID | 2992 |
| Uniprot ID | GLYG_HUMAN |
| Accession Number | AAH00033 |
| Immunogen | Human |
| Immunogen Region | 1-333aa |
| Immunogen Sequence | MHHHHHHMAS MTGGQQMGRD LYDDDDKDRW GSMTDQAFVT LTTNDAYAKG ALVLGSSLKQ HRTTRRLVVL ATPQVSDSMR KVLETVFDEV IMVDVLDSGD SAHLTLMKRP ELGVTLTKLH CWSLTQYSKC VFMDADTLVL ANIDDLFDRE ELSAAPDPGW PDCFNSGVFV YQPSVETYNQ LLHLASEQGS FDGGDQGILN TFFSSWATTD IRKHLPFIYN LSSISIYS |
Additional Info
| Tissue Specificity | Highly expressed in skeletal muscle and heart, with lower levels in brain, lung, kidney and pancreas. |
| Post Translational Modifications | Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195. Phosphorylated. |
| Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase. |
| Protein Name | Glycogenin-1Gn-1Gn1 |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3785653Reactome: R-HSA-3814836Reactome: R-HSA-3828062Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | CytoplasmNucleusLocalizes To Glycogen Granules (Glycosomes) In The CytoplasmCytosolic Localization Is Dependent On The Actin Cytoskeleton |
| Alternative Protein Names | Glycogenin-1 proteinGn-1 proteinGn1 proteinGYG1 proteinGYG protein |
Information sourced from Uniprot.org