Human Glycogenin 1 protein (Recombinant) (His-T7-Tag) (STJP016492)

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STJP016492
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Glycogenin 1-His-T7-Tag protein was developed from e.coli and has a target region of His-T7-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: GYG1
Gene ID: 2992
Uniprot ID: GLYG_HUMAN
Immunogen Region: 1-333aa
Accession Number: AAH00033
Immunogen: Human
Immunogen Sequence: MHHHHHHMAS MTGGQQMGRD LYDDDDKDRW GSMTDQAFVT LTTNDAYAKG ALVLGSSLKQ HRTTRRLVVL ATPQVSDSMR KVLETVFDEV IMVDVLDSGD SAHLTLMKRP ELGVTLTKLH CWSLTQYSKC VFMDADTLVL ANIDDLFDRE ELSAAPDPGW PDCFNSGVFV YQPSVETYNQ LLHLASEQGS FDGGDQGILN TFFSSWATTD IRKHLPFIYN LSSISIYS
Tissue Specificity Highly expressed in skeletal muscle and heart, with lower levels in brain, lung, kidney and pancreas.
Post Translational Modifications Self-glycosylated by the transfer of glucose residues from UDP-glucose to itself, forming an alpha-1,4-glycan of around 10 residues attached to Tyr-195. Phosphorylated.
Function Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.
Protein Name Glycogenin-1
Gn-1
Gn1
Database Links Reactome: R-HSA-3322077
Reactome: R-HSA-3785653
Reactome: R-HSA-3814836
Reactome: R-HSA-3828062
Reactome: R-HSA-5357609
Reactome: R-HSA-6798695
Reactome: R-HSA-70221
Cellular Localisation Cytoplasm
Nucleus
Localizes To Glycogen Granules (Glycosomes) In The Cytoplasm
Cytosolic Localization Is Dependent On The Actin Cytoskeleton
Alternative Protein Names Glycogenin-1 protein
Gn-1 protein
Gn1 protein
GYG1 protein
GYG protein

Information sourced from Uniprot.org

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