Human Glutathione S-transferase alpha 1/GSTA1 protein (Recombinant) (No-Tag) (STJP016585)

SKU:
STJP016585
$173.19 - $896.31
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Host: E.coli
Applications: SDS-PAGE/Enzyme Activity
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Glutathione S-transferase alpha 1/GSTA1-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity: Specific activity is > 35, 000pmol/min/ug, and is defined as the amount of enzyme that conjugate 1.0 u mole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C.
Gene Symbol: GSTA1
Gene ID: 2938
Uniprot ID: GSTA1_HUMAN
Immunogen Region: 1-222aa
Accession Number: NP_665683
Immunogen: Human
Immunogen Sequence: MAEKPKLHYF NARGRMESTR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYIEGIA DLGEMILLLP VCPPEEKDAK LALIKEKIKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEEARKIF RF
Tissue Specificity Liver.
Function Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
Protein Name Glutathione S-Transferase A1
13-Hydroperoxyoctadecadienoate Peroxidase
Androst-5-Ene-3 -17-Dione Isomerase
Gst Ha Subunit 1
Gst Class-Alpha Member 1
Gst-Epsilon
Gsta1-1
Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed
Database Links Reactome: R-HSA-156590
Reactome: R-HSA-189483
Reactome: R-HSA-9748787
Reactome: R-HSA-9818027
Cellular Localisation Cytoplasm
Alternative Protein Names Glutathione S-Transferase A1 protein
13-Hydroperoxyoctadecadienoate Peroxidase protein
Androst-5-Ene-3 -17-Dione Isomerase protein
Gst Ha Subunit 1 protein
Gst Class-Alpha Member 1 protein
Gst-Epsilon protein
Gsta1-1 protein
Gth1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed protein
GSTA1 protein

Information sourced from Uniprot.org