Human Glutathione Reductase protein (Recombinant) (His-Tag) (STJP017442)

SKU:
STJP017442
£134.50 - £738.50
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Short Description :Recombinant-Human Glutathione Reductase-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:Enzyme Activity/SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Immunoreactivity:Specific activity is > 45unit/mg. The unit definition for glutathione reductase activity may be expressed in terms of the oxidation of NADPH or the reduction of GSSG since their molar ratio is 1:1. One unit of glutathione reductase oxidizes 1 umol of
Gene Symbol:GSR
Gene ID:2936
Uniprot ID:GSHR_HUMAN
Accession Number:NP_000628
Immunogen:Human
Immunogen Region:43-522aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAMACRQ EPQPQGPPPA AGAVASYDYL VIGGGSGGLA SARRAAELGA RAAVVESHKL GGTCVNVGCV PKKVMWNTAV HSEFMHDHAD YGFPSCEGKF NWRVIKEKRD AYVSRLNAIY QNNLTKSHIE IIRGHAAFTS DPKPTIEVSG KKYTAPHILI ATGGMPSTPH ESQIPGASLG ITSDGFFQLE ELPGRSVIVG AGYIAVEM
Function Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.
Protein Name Glutathione Reductase - Mitochondrial
Gr
Grase
Database Links Reactome: R-HSA-2408550 P00390-2
Reactome: R-HSA-3299685
Reactome: R-HSA-499943 P00390-2
Reactome: R-HSA-5628897 P00390-2
Reactome: R-HSA-9818027 P00390-2
Cellular Localisation Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic: Cytoplasm
Alternative Protein Names Glutathione Reductase - Mitochondrial protein
Gr protein
Grase protein
GSR protein
GLUR protein
GRD1 protein

Information sourced from Uniprot.org