Human GDF3 protein (Recombinant) (N-His) (STJP006070)

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STJP006070
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GDF3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GDF3
Gene ID: 9573
Uniprot ID: GDF3_HUMAN
Immunogen Region: Ala251-Gly364
Immunogen: Homo sapiens (Human)
Function Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto.
Protein Name Growth/Differentiation Factor 3
Gdf-3
Cellular Localisation Secreted
Cytoplasm
Mainly Accumulated In The Cytoplasm
Alternative Protein Names Growth/Differentiation Factor 3 protein
Gdf-3 protein
GDF3 protein
UNQ222 protein
PRO248 protein

Information sourced from Uniprot.org