Function | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto. |
Protein Name | Growth/Differentiation Factor 3Gdf-3 |
Cellular Localisation | SecretedCytoplasmMainly Accumulated In The Cytoplasm |
Alternative Protein Names | Growth/Differentiation Factor 3 proteinGdf-3 proteinGDF3 proteinUNQ222 proteinPRO248 protein |
Information sourced from Uniprot.org