| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GDAP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GDAP1 |
| Gene ID: | 54332 |
| Uniprot ID: | GDAP1_HUMAN |
| Immunogen Region: | Lys25-Ala316 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Regulates the mitochondrial network by promoting mitochondrial fission. |
| Protein Name | Ganglioside-Induced Differentiation-Associated Protein 1Gdap1 |
| Database Links | Reactome: R-HSA-9603798 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane ProteinCytoplasm |
| Alternative Protein Names | Ganglioside-Induced Differentiation-Associated Protein 1 proteinGdap1 proteinGDAP1 protein |
Information sourced from Uniprot.org