Human GCA protein (Recombinant) (His-Tag) (STJP017024)

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STJP017024
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human GCA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol 0.1M NaCl
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: GCA
Gene ID: 25801
Uniprot ID: GRAN_HUMAN
Immunogen Region: 1-217aa
Accession Number: NP_036330.1
Immunogen: Human
Immunogen Sequence: MAYPGYGGGF GNFSIQVPGM QMGQPVPETG PAILLDGYSG PAYSDTYSSA GDSVYTYFSA VAGQDGEVDA EELQRCLTQS GINGTYSPFS LETCRIMIAM LDRDHTGKMG FNAFKELWAA LNAWKENFMT VDQDGSGTVE HHELRQAIGL MGYRLSPQTL TTIVKRYSKN GRIFFDDYVA CCVKLRALTD FFRKRDHLQQ GSANFI
Tissue Specificity Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Function Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Protein Name Grancalcin
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Cytoplasmic Granule Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Primarily Cytosolic In The Absence Of Calcium Or Magnesium Ions
Relocates To Granules And Other Membranes In Response To Elevated Calcium And Magnesium Levels
Alternative Protein Names Grancalcin protein
GCA protein
GCL protein

Information sourced from Uniprot.org