Human GATM protein (Recombinant) (N-His) (STJP009624)

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STJP009624
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Short Description :Recombinant-Human GATM-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:GATM
Gene ID:2628
Uniprot ID:GATM_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Glu76-Asp423
Function Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives. Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain (Probable).
Protein Name Glycine Amidinotransferase - Mitochondrial
L-Arginine -Glycine Amidinotransferase
Transamidinase
Database Links Reactome: R-HSA-71288
Cellular Localisation Isoform 1: Mitochondrion Inner Membrane
Peripheral Membrane Protein
Intermembrane Side
Probably Attached To The Outer Side Of The Inner Membrane
Isoform 2: Cytoplasm
Alternative Protein Names Glycine Amidinotransferase - Mitochondrial protein
L-Arginine -Glycine Amidinotransferase protein
Transamidinase protein
GATM protein
AGAT protein

Information sourced from Uniprot.org